Roger Guillemin, 100, Nobel-Winning Scientist Stirred by Rivalries, Dies
Health

Roger Guillemin, 100, Nobel-Winning Scientist Stirred by Rivalries, Dies

Roger Guillemin, a neuroscientist who was a co-discoverer of the unexpected hormones with which the brain controls many bodily functions, died on Wednesday at a senior living facility in San Diego. He was 100.His death was confirmed by his daughter Chantal Guillemin.Dr. Guillemin’s career was marked by two spectacular competitions that ruffled the staid world of endocrinological research. The first was a 10-year tussle with his former partner, Andrew V. Schally, which ended in a draw when the two shared half of the Nobel Prize in Physiology or Medicine in 1977. (The other half went to the American medical physicist Rosalyn Yalow for unrelated research.)The second competition began shortly afterward when Wylie Vale Jr., Dr. Guillemin’s longtime collaborator and protégé, set up a rival labor...
The fearless mindset of the Warriors’ Brandin Podziemski: ‘He’s got a delusion to him’
Sports

The fearless mindset of the Warriors’ Brandin Podziemski: ‘He’s got a delusion to him’

SAN FRANCISCO — Nearly a year ago on the dot, Mike Dunleavy, the Golden State Warriors’ future general manager, and Kent Lacob, an ascending front office personnel voice, hopped in a car and made the quick 50 mile trip south to Santa Clara’s campus.They were primarily there to see Maxwell Lewis, the possible lottery pick out of Pepperdine. Lewis played fine. He’d eventually get selected 40th in the 2023 NBA Draft. But he wasn’t the best player on the floor. Brandin Podziemski, a 6-foot-4 guard who was only beginning to creep onto the draft radar, made every significant play to lead Santa Clara to victory. His 23 points mattered. But it was the 18 rebounds that had Dunleavy’s and Lacob’s antennas up.“Mike and I walked out of the game like, ‘Um, that guy might be a first-round pick,'” Lacob ...
A Billionaire Bought a Chunk of Manchester United. Now He Has to Fix It.
World

A Billionaire Bought a Chunk of Manchester United. Now He Has to Fix It.

The process was six months old and already starting to wear on Jim Ratcliffe, the British billionaire, the first time he brought out the Champagne to toast his purchase of Manchester United. But even that celebration, at the Monaco Grand Prix in May, proved premature.There was no deal. Not yet.Doing one was never going to be easy. Mostly, that was because any potential sale for United offered a tantalizing marriage of money, power and history: Mr. Ratcliffe, the wealthy chairman of INEOS, the petrochemicals giant, had supported Manchester United since he was a boy. United, the most decorated club in English soccer, was one of the most iconic brands in global sports. And the Premier League, to which it belonged, was the richest soccer league in the world.What ensued was an auction as unpred...
New Freighters Could Ease Red Sea Cargo Disruptions
Business

New Freighters Could Ease Red Sea Cargo Disruptions

After the Houthi militia started attacking container ships in the Red Sea last year, the cost of shipping goods from Asia soared by over 300 percent, prompting fears that supply chain disruptions might once again roil the global economy.The Houthis, who are backed by Iran and control northern Yemen, continue to threaten ships, forcing many to take a much longer route around Africa’s southern tip. But there are signs that the world will probably avoid a drawn-out shipping crisis.One reason for the optimism is that a huge number of container ships, ordered two to three years ago, are entering service. Those extra vessels are expected to help shipping companies maintain regular service as their ships travel longer distances. The companies ordered the ships when the extraordinary surge in worl...
Nvidia Earnings Show Soaring Profit and Revenue Amid AI Boom
Technology

Nvidia Earnings Show Soaring Profit and Revenue Amid AI Boom

Nvidia, the kingpin of chips powering artificial intelligence, on Wednesday released quarterly financial results that reinforced how the company has become one of the biggest winners of the artificial intelligence boom, and it said demand for its products would fuel continued sales growth.The Silicon Valley chip maker has been on an extraordinary rise over the past 18 months, driven by demand for its specialized and costly semiconductors, which are used for training popular A.I. services like OpenAI’s ChatGPT chatbot. Nvidia has become known as one of the “Magnificent Seven” tech stocks, which, including others like Amazon, Apple and Microsoft, have helped power the stock market.Nvidia’s valuation has surged more than 40 percent to $1.7 trillion since the start of the year, turning it into...
Study of Patients With a Chronic Fatigue Condition May Offer Clues to Long Covid
Health

Study of Patients With a Chronic Fatigue Condition May Offer Clues to Long Covid

Jennifer Caldwell was active and energetic, working two jobs and taking care of her daughter and her parents, when she developed a bacterial infection that was followed by intense lightheadedness, fatigue and memory problems.That was nearly a decade ago, and she has since struggled with the condition known as myalgic encephalomyelitis/chronic fatigue syndrome, or ME/CFS. Ms. Caldwell, 56, of Hillsborough, N.C., said she went from being able to ski, dance and work two jobs as a clinical research coordinator and a caterer to needing to stay in bed most of every day.“I haven’t been right since, and I haven’t worked a day since,” said Ms. Caldwell, whose symptoms include severe dizziness whenever her legs are not elevated.The condition has also “messed me up cognitively,” she said. “I can’t re...
‘His legs have gone’: Unpicking the four words no footballer wants to hear
Sports

‘His legs have gone’: Unpicking the four words no footballer wants to hear

Last season, it was a Brazilian midfielder at Liverpool. This season, it’s been his international team-mate at Manchester United.“I think Casemiro’s legs have gone,” Jamie Carragher told the Covering Liverpool podcast in October. “I noticed it last season at Anfield and I didn’t like what I saw. It took me back to watching Fabinho last year for Liverpool. I want to be the first to say it (about Casemiro). I don’t want to say it when everyone else is saying his legs have gone.”Regardless of who said what and when, Carragher — who played for Liverpool until he retired at age 35 — is not a lone voice in this debate, and Fabinho and Casemiro are far from the only players singled out for seemingly having lead in their boots.Any footballer over the age of 30 who is struggling for form leaves the...
Overlooked No More: Pierre Toussaint, Philanthropist and Candidate for Sainthood
World

Overlooked No More: Pierre Toussaint, Philanthropist and Candidate for Sainthood

This article is part of Overlooked, a series of obituaries about remarkable people whose deaths, beginning in 1851, went unreported in The Times.In 1849, Mary Ann Schuyler, a wealthy New Yorker, was reminded fondly of her longtime hairdresser, Pierre Toussaint, while visiting a Roman Catholic chapel in Europe. “Send my love to him,” she wrote to her sister, Hannah Farnham Sawyer Lee. “Tell him I think of him very often and never go to one of the churches of his faith without remembering my own St. Pierre.”By then, Toussaint, 68, had built a reputation as “the Vidal Sassoon of his day,” as Daniel W. Bristol Jr. wrote in “Knights of the Razor: Black Barbers in Slavery and Freedom” (2015): He had mastered the in-vogue hairstyles of the French — powdered hair, or false hair added on — as well ...
Walmart’s Earnings Rise on Holiday Sales and Surging E-Commerce
Business

Walmart’s Earnings Rise on Holiday Sales and Surging E-Commerce

The NumbersWalmart said its comparable store sales were up 4 percent in the three months that ended in late January compared with the year before. The number of transactions at Walmart rose 4.3 percent, but the average ticket price slightly decreased 0.3 percent, a sign that shoppers spent a little less on shopping trips. The retailer’s online U.S. sales increased 17 percent, and its online global sales jumped 23 percent, surpassing $100 billion. Losses for the e-commerce business were slowing as the company spent less on fulfillment costs, John David Rainey, Walmart’s chief financial officer, said in an interview. He added that more customers were using Walmart’s delivery services, helping to reduce costs.“Instead of a Walmart delivery being delivered to one house on a cul-de-sac, now we’...
Inside the Funding Frenzy at Anthropic, One of A.I.’s Hottest Start-Ups
Technology

Inside the Funding Frenzy at Anthropic, One of A.I.’s Hottest Start-Ups

Last May, Anthropic, one of the world’s hottest artificial intelligence start-ups, raised $450 million from investors including Google and Salesforce. It was the beginning of an astonishing funding spree.By August, Anthropic had landed $100 million from two Asian telecoms. Then Amazon committed $4 billion to it, followed by $2 billion more from Google.This month, the venture capital firm Menlo Ventures closed a deal to invest $750 million in Anthropic.All told, the A.I. start-up hauled in $7.3 billion in a year. Its five funding deals stood out not just for their speed and size, but for their unusual structures.In one of those deals, Anthropic agreed to use technology such as chips and cloud computing services from the companies that invested in it. That meant, in effect, that some of the ...